DUBAI: Iranian Supreme Leader Ayatollah Ali Khamenei was killed in a major attack by Israel and the United States, Iranian state media confirmed early Sunday, throwing the future of the Islamic Republic into doubt and raising the risk of regional instability.

President Donald Trump announced the death hours earlier, saying it gave Iranians their “greatest chance” to “take back” their country.

State media reported that the 86-year-old was killed in an airstrike targeting his compound in downtown Tehran. Satellite photos from Airbus showed that the site was heavily bombed.